Madhumukta (Liquid & Tablet)

Madhumukta (Liquid & Tablet)

(Improves Pancreatic Function – Useful in Diabetic Complications)

Introduction to Diabetes:
    Imbalance of sugar/carbohydrates metabolism is diabetes. The food stuff is converted to essential sugar for caloric utilization of the body. Insulin, a hormone secreted by the pancreas plays a key role in this conversion. It aids the sugar in the form of Glycogen to get stored in the liver. In case the blood sugar level drops, the glycogen is reconverted to sugar. This is how it helps to prevent hypoglycemia and related symptoms. In diabetics, the production of insulin is deficient or completely clogged. Inadequate production of insulin ends up in increased blood sugar and finally settles diabetes.

Causes:
• Sedentary lifestyle
• Excess consumption of milk and dairy products
• Derivatives of sugarcane in excess
• Consuming flesh of aquatic animals beyond certain limits
• Newly harvested grains repeatedly
• Items which increase Kapha

Symptoms:
• Increased frequency of urine
• Fatigue
• Constant feeling of thirst
• Burning micturition
• Sudden loss of weight

Types of Diabetes:
• Juvenile diabetes or Insulin dependent diabetes (Also called Type 1 or IDD)
• Acquired diabetes or Non-insulin dependent diabetes (Type 2 / NIDD)
• Gestational diabetes

After effects of diabetes:
• Coronary artery disease
• Diseases of Central Nervous System
• Renal disease
• Ophthalmic (retinal) disease
• Disease of the feet
• Ear diseases
• Skin disorders
• Deterioration of cognitive functions
• Increase in Cholesterol, triglycerides
• Incidence of atherosclerosis

Mechanism of action:
• Stimulating insulin
• Preventing carbohydrate absorption
• Metabolizing the dietary intake
• Burning excess calories
• Gradually reducing blood sugar level
• Improving the glucose tolerance
• Preventing onslaught of free radicals

MADHUMUKTA - Liquid
Each 10 ml Liquid contain extracts derived from:
Guduchi (Tinospora cordifolia), Meshshringi (Gymnema sylvestre), Nimb Leaf (Azadirachta indica), Saptarangi (Casearia esculenta) Each 250 mg; Amalaki (Phyllanthus emblica), Bilva Leaf (Aegle marmelos), Haridra (Curcuma longa), Jamun Seed (Eugenia jambolana), Karvellak (Momordica charantia), Kiratikta (Swertia chirata), Kulinjan (Alpinia galanga), Trivrut Root (Operculina turpethum), Vijaysar (Pterocarpus marsupium), Yashtimadhu (Glycyrrhiza glabra) Each 125 mg

Guduchi (Tinospora cordifolia) : This herb is a master-key for treating diabetes. There are many herbs to reduce blood sugar but very few contribute to improve the function of pancreas. Guduchi ranks top in this segment. It is proven remedy to treat diabetic retinopathies, neuropathies, gastropathies, nephropathies, diabetic foot injuries, diabetic complications associated with CNS, onslaught on the liver, heart, cholesterol, diabetic seminal weakness, osteoporosis etc. The clinical miraculous effect of this herb is that it can even prevent the effect of diabetes on foetal development. Insulin is secreted by ß cells in the pancreas whereas some autoimmune cells destroy them and trigger the disease. This herb has some exclusive properties to deactivate the autoimmune cells and thereby help to improve the insulin secretion.

Meshshringi (Gemnema sylvestere) : The herb is also termed as Gudmar where ‘Gud’ indicates sweet and ‘Mar’ indicates antagonist activity. Therefore the word ‘Gudmar’ indicates the activity as “antagonist of sweet”. The herb acts by different modes. 1) It regenerates the cells of islets of langerhans in the pancreas. 2) Increases the secretion of insulin. 3) Prevents the absorption of sugar from at the intestinal level. 4) The converted glucose from glycogen is utilized by the muscles and thereby helps to maintain the blood sugar level up to the desired healthy level.

Nimb Leaf (Azadirachta indica) : Neem reduces the requirement of insulin from 60 to 70%, hence it is especially effective in insulin dependent diabetes. Diabetes causes hardness in the blood vessels termed as atherosclerosis. This condition obstructs the oxygenated blood flow to the vital organs of the body which may lead to gangrene and finally amputation. The property of Neem improves the circulation and minimizes the chances of such consequence. Diabetes also complicates many skin disorders. The effect of Neem in treating skin ailments is known to every Indian.

Saptarangi (Casearia esculenta) : The herb, Casearia esculenta is especially effective in treating Insulin resistance (IR), which also aids the uptake of blood sugar by the muscular tissue and helps in lowering the blood sugar levels. The increased sugar causes onslaught of free radicals on the organs like liver, kidneys and retina. The antioxidants in this herb are capable to prevent this attack and protect these vital organs.

Amalaki (Phyllanthus emblica) : The fruit is a natural source of vitamin C which imparts supreme immunity. Regular consumption of this fruit reduces the fasting, postprandial blood sugar and also glycosylated hemoglobin. Apart from that, it has lipid lowering effect which checks the increased cholesterol and triglycerides.

Bilwa patra (Aegle marmelos) : Diabetic neuropathies cause severe pain in various areas of the body. The leaves of this herb are especially effective in treating the neuropathies and keep a check on the tenderness. Apart from this, it is also effective in preventing the diabetic nephropathies and prevent the formation of early cataract, which is a consequence of diabetes.

Haridra (Curcuma longa) : It is a common culinary item found in every house in India and recognized as Haldi or turmeric. Its use in cancer, inflammations, blood occlusion due to thrombus, atherosclerosis, neuro-protection, memory enhancement, Parkinson’s disease, osteo-arthritis, coronary artery disease, infection, ageing disorder, psoriasis and epilepsy have been strongly documented. In case of pregnancy, it is effective in proper closure of the neural tube and thereby protect the consequences like spina bifida.

Jamun seeds (Syzygium cumini) : This fruit is considered to be very useful in diabetics. Practically, the seeds of this fruit are benefitting, not the pulp or juice. The pulp and juice increase the blood sugar level and can create a serious situation for diabetics. The use of seeds in treating diabetes is well known since long time. In fact, the hypoglycemic activity of these seeds was known even before insulin was discovered. It is studied that Jamun seeds increase the insulin level in the blood by three times and also keeps check on serum cholesterol.

Karela (Momordica charantia) : This fruit stimulates the secretion of insulin from pancreas, prevents the absorption of glucose from the intestine and also improves the uptake by muscles. This 3 way action plays a useful role in the treatment of diabetes.

Kirattikta (Swertia chirata) : Whether a case of diabetes or not, dropping blood sugar level below 70 mg/dl is called hypoglycemia. Care must always be taken to prevent arriving to such situation, particularly while treating diabetes. Hypoglycemia can lead to symptoms like mental confusion, giddiness, tremors, appetite, headache, mental irritability, bradycardia, palpitation, pallor, profuse sweating, and weakness. This herb has a peculiar property that it reduces the blood sugar level but doesn’t allow to drop below normal level.

Kulinjan (Alpinia galanga) : Apart from hypoglycemic activity, this herb imparts protective effect of free radicals generated due to diabetes on the kidneys and keeps check cholesterol levels.

Trivrut (Operculina turpethum) : The complications of diabetes include burning palms and feet, indigestion, constipation and dryness of throat. This herb is effective in tackling these symptoms.

Vijaysar (Pterocarpus marsupium) : It improves the absorption of sugar from circulating blood to the muscles which lowers the blood sugar levels. This absorption improves muscular strength, overcomes fatigue, muscular weakness, cramps and restores energy level. It also enhances the insulin secretion, controls blood lipid levels and thereby manages various aspects of diabetes.

Yashtimadhu (Glycyrrhiza glabra) : Out of thousands of herbs from the nature’s treasury, very few herbs are sweet in taste, one of which is Yashtimadhu. It will be shocking to know that how sweet herb could be acting on diabetes. Yashtimadhu contains an active principle named as Amorfrutin. Current research at the Max Planck Institute for Molecular Genetics in Berlin has found that Liquorice root contains amorfrutins. Amorfrutins exhibit anti-inflammatory properties, decrease blood sugar levels and above all they accomplish this without significant adverse effects. Amofrutins were found to bind and activate a nuclear receptor protein (peroxisome proliferator-activated receptor gamma (PPARγ)) that affects glucose and lipid metabolism; important factors in type 2 Diabetes.

MADHUMUKTA Tablets 
Each coated tablet contains powders of :
Daruharidra (Berberis aristata), Devdar (Cedrus deodara), Guduchi (Tinospora cordifolia), Jamun Seed (Eugenia jambolana), Karvellak (Momordica charantia), Nagarmotha (Cyperus rotundus), Triphala Each 75 mg; Micronized and Potentised with Guduchi (Tinospora cordifolia) Q. S.

Brief action of the ingredients in Madhumukta tablets :
Apart from Guduchi, Jamun seed and Karela, the tablets contain few additional ingredients like Daruharidra, Devdar, Nagarmotha and Triphala. The therapeutic activities of these herbs along with a nanonizing manufacturing technique are the special attributes in case of tablets. Triturating the composition with active herbal ingredient potentizes the formula and contributes to its dynamic clinical profile. The ingredients in liquid and tablets are different and their mode of action is also different. Hence they can’t be taken as a substitute for each other. The tablets contain volatile oils which could not be incorporated in liquid as they may lose the properties due to boiling. Diabetics are recommended to use both simultaneously for achieving optimum benefits.

Daruharidra (Berberis aristata) : The herb is helpful in controlling hyperglycemia and simultaneously maintains the equilibrium of serum lipids. LDL and HDL are the two types of lipids in the body. In relation to cardiac health, LDL (Low Density Lipoproteins also called as Bad Cholesterol) should be less than 100 mg/deciliter. There are many herbs effective in lowering the LDL but only few can increase HDL (High Density Lipoproteins or Good Cholesterol). The HDL should be more than 60 mg/dl and surprisingly Daruharidra (Berberis aristata) possesses this unique property. Hence this herb is a boon to diabetics to prevent circulatory complications and thereby protect the heart.

Deodar (Cedrus deodara) : Generally liver problem is always correlated to alcoholism. But diabetes also has a serious impact on liver causing Fatty liver. This herb has immense potential to repair fatty liver due to diabetes. SGOT, SGPT, Cholesterol, Triglycerides are the biochemical parameters to determine liver health and this herb brings all these parameters to normal level. Apart from this, this herb possesses supreme antioxidant properties.

Nagarmotha (Cyperus rotundus) : The mode of action of this herb is quite different. Due to Alpha-glucosidase inhibitors and Alfa Amylase inhibitors, it allows the absorption of dietary sugars in the blood very slowly. Hence, it role in post-prandial sugar control is significant. In such situation, the dietary carbohydrate gives stimulation to the insulin for longer duration. Burning palms, feet, indigestion, obesity and prevention from infection are special attributes of this herb.

Triphala (Equal quantities of 3 herbs viz. Haritaki, Bibhitaki and Amalaki) : Apart from sugar lowering property, there are many hidden benefits in this composition. The outstanding properties are supreme antioxidant, anti-inflammatory, anti-pyretic, analgesic, anti-bacterial, anti-mutagenic, wound healing, anti-cancer, anti-depressant, anti-ageing, radio-protective etc. The said composition is popularly used to treat constipation, anorexia, hyperacidity and for improving vision.

Indications:
• Known Type 2 Diabetics
• Those having family history of diabetes
• Those with pre-diabetic symptoms
• Gestational diabetes
• Type 1 diabetics to minimize the Insulin requirement
• Obese individuals to keep check on weight
• Individuals with hypercholesterolemia

Diet & Lifestyle recommendations:
• Avoid sugar based products
• Avoid milk and dairy products
• Refrain from newly harvested grains
• Perform moderate and regular exercise
• Avoid flesh of aquatic animals
• Items which increase Kapha
• Do not sleep during day time, particularly after meals
• Wake up early in the morning
• Avail low-fat diet

Dosage: 
MADHUMUKTA Liquid 15 ml twice daily with 2 tablets of MADHUMUKTA Tablets on empty stomach. Skip the daily dose once in a week or as directed by the physician. The dosage may be adjusted/ modified as per the severity of the disorder.

WHY WEEKLY OFF?
Consuming any medicine daily for long time reduces the therapeutic effect as the body becomes used to and reduces the response to the medication. Keeping a weekly off, triggers the activity with improved efficacy.

PRECAUTIONS:
Do not stop the previous medication abruptly. Keep an eye on the sugar levels regularly. If the blood sugar level drops, it may lead to hypoglycemia. Hence it is always advised to keep a pouch of glucose or a chocolate for tackling the situation. Consuming MADHUMUKTA after meals may seldom cause hyperacidity. Hence, it is recommended before meals with more dilution with cold water. Experiencing hyperacidity is indeed a sign of positive action of the formula. After all pancreatic enzymes are also a derivatives of Pitta according to Ayurveda.

Presentation: 
Tablet: 120 tablets
Liquid: 500 ml & 1000 ml PET bottle